Unlike our peer institutions, the UNC Eshelman School of Pharmacy conducts a wide range of advanced research that aligns with five phases of the drug discovery, development and delivery cycle. Each phase is represented by one of five division within the School.

Faculty and graduate students alike are encouraged to work with their peers within the School and the University to further realize research goals in discovery, preclinical and clinical development of therapeutic agents, optimum delivery of drug therapy, evaluation of health and therapeutic outcomes of novel drug therapies and technologies, as well as regulatory policies.

 

Corbin-Bryan

Corbin Bryan

Northern High School

Liquid Phase Short Peptide Synthesis

Faculty Mentor: Albert Bowers, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Alexander-Kyu

Alexander Kyu

Raleigh Charter High School

RVV-X, RVV-V and Drug Delivery

Faculty Mentor: Jian Liu, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Anthony-Kyu

Anthony Kyu

Raleigh Charter High School

Russell’s Viper Venom Coagulation and Stability

Faculty Mentor: Jian Liu, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Jonathan-Stepp

Jonathan Stepp

Trinity School of Durham and Chapel Hill
Faculty Mentor: Andrew Lee, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Ponni-Theetharappan

Ponni Theetharappan

Enloe High School

Splicing Kinase Data Analysis and QSAR Modeling

Faculty Mentor: Alex Tropsha, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Benjamin-Wu

Benjamin Wu

Trinity School of Durham and Chapel Hill

Oct4 Locus Activation: Synthetic Recruitment of Transcriptional Activators

Faculty Mentor: Nate Hathaway, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Josie-Cranfill

Josie Cranfill

Trinity School of Durham and Chapel Hill
Faculty Mentor: Sam Lai, Ph.D.
Division of Pharmacoengineering and Molecular Pharmaceutics

Luke-Garges

Luke Garges
Trinity School of Durham and Chapel Hill

Stem Cells: The Oncologist’s Friend

Faculty Mentor: Shawn Hingtgen, Ph.D.
Division of Pharmacoengineering and Molecular Pharmaceutics

William-Mangum

William Mangum

Northern High School

Acetylated Dextran and Targeted Drug Delivery

Faculty Mentor: Kristy Ainslie, Ph.D.
Division of Pharmacoengineering and Molecular Pharmaceutics

Acelynn-Barefoot

Acelynn Barefoot

Northern High School
Faculty Mentor: Dhiren Thakker, Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Caroline-Blythe

Caroline Blythe

Woods Charter School

Both Sides of the Cancer Equation

Faculty Mentor: Bill Zamboni, Pharm.D., Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Hunter-Hughes

Hunter Hughes

Woods Charter School

Development of a Polysaccharide Polymer-based Product for Chemotherapy Spills

Faculty Mentor: Bill Zamboni, Pharm.D., Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Lindsey-Kirby

Lindsey Kirby

Trinity School of Durham and Chapel Hill

Preemptive Genotyping & Pharmacogenomics

Faculty Mentor: Tim Wiltshire, Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Mallory-Storrie

Mallory Storrie

Northwood High School

Pharmacokinetic Studies of a Novel Nanoparticle Formulation of Cisplatin in Mice

Faculty Mentor: Bill Zamboni, Pharm.D., Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Salem-Williams

Salem Williams

Northwood High School

The Effect of Clinical Trial Studies on the Outcome of Patient Treatment and Care

Faculty Mentor: Bill Zamboni, Pharm.D., Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Lakshmi-Immaneni

Meenakshi Immaneni

STEM Early College at NC A&T

Development of a Fluorescence-based Assay for a Methyl-lysine Reader Chromodomain

Faculty Mentor: Stephen Frye, Ph.D.
Center for Integrative Chemical Biology and Drug Discovery

Lena-Cohen

Lena Cohen

Chapel Hill High School
Faculty Mentor: Elena Batrakova, Ph.D.
Center for Nanotechnology in Drug Delivery

Dalal Azzam

Green Hope High School

Synthesis of Cephalosporin Analogues Through Amide Coupling for Evaluation of Activity Against Mycobacterium Tuberculosis

Faculty Mentor: Jeff Aubé, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Erin Blanding

Sun Valley High School

Site-specific Histone Ubiquitylation to Study Chromatin Signaling

Faculty Mentor: Robert McGinty, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Tyler Deegan

Woods Charter School

Liposome Composition Effects on Phospholipase Activity

Faculty Mentor: Qisheng Zhang, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Michael McGirt

Hillside High School

The Discovery of Anti-Chikungunya Targets and Drugs using Text-Mining

Faculty Mentor: Alex Tropsha, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Hannah Myatt

Home School

Effect of HPLC Conditions on Low Molecular Weight Heparin Analysis

Faculty Mentor: Jian Liu, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Clara To

East Chapel Hill High School

IL10 Trap Expression, Purification, and Characterization

Faculty Mentor: Rihe Liu, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Elijah Whitfield

First Flight High School

Phage Display for Discovery of Tool Peptide Inhibitors for Cancer Targets KRAS and CIB1

Faculty Mentor: Kenneth Pearce, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Alexander DeWalle

Raleigh Charter High School

Determining the Optimal PEG Length in Order to Limit Immune Complex Formation in a Vaccinated Mouse Model

Faculty Mentor: Sam Lai, Ph.D.
Division of Pharmacoengineering and Molecular Pharmaceutics

Michael Marand

Panther Creek High School

The Use of Modified Neural Stem Cells as a Therapeutic Carrier to Treat Brain Tumors

Faculty Mentor: Shawn Hingtgen, Ph.D.
Division of Pharmacoengineering and Molecular Pharmaceutics

Olivia Osborne

Woods Charter School

Gene Editing of Vaginal Bacteria Using Engineered Bacteriophage

Faculty Mentor: Sam Lai, Ph.D.
Division of Pharmacoengineering and Molecular Pharmaceutics

Alexandra Simpson

Hillside High School

Novel Formulations of HIV Prevention Drugs

Faculty Mentor: Rahima Benhabbour, Ph.D.
Division of Pharmacoengineering and Molecular Pharmaceutics

Sara Eve

Northwood High School

Evaluating the Efficiencies and Deficiencies of Nanoparticle Tumor Delivery and Disposition

Faculty Mentor: Bill Zamboni, Pharm.D., Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Megan Kanaby

Cardinal Gibbons High School

Evaluating the Efficiencies and Deficiencies of Nanoparticle Delivery and Distribution in Tumors

Faculty Mentor: Bill Zamboni, Pharm.D., Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Ryan Kemper

Green Hope High School

Determining if MATE 1 in Endometrial Cancer Cells is a Factor in the Efficacy of Cancer Treatments in Conjunction with the Drug Metformin

Faculty Mentor: Dhiren Thakker, Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Malaika Kimmons

Apex Friendship High School

Imaging of Monoclonal Antibodies Using Bioluminescence Resonance Energy Transfer (BRET)

Faculty Mentor: Yanguang Cao, Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Daniel Mangum

Trinity School of Durham & Chapel Hill

Analyzing A sequence of Events: PGX Education in Future Pharmacists

Faculty Mentor: Amber Frick, Pharm.D., Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Zoe Miller

Chapel Hill High School

Polycystic Kidney Disease Alters Protein Expression of Drug Transporters in the Liver

Faculty Mentor: Kim Brouwer, Pharm.D., Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Coleman Mitchell

Cary Academy

Applications and Importance of Pharmacogenomics/Pharmacogenetics and Precision Medicine

Faculty Mentor: Tim Wiltshire, Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

William Jones

Charles B. Aycock High School

Rural Healthcare and It’s Influence on Access, and Substance Abuse

Faculty Mentor: Jon Easter, R.Ph.
Division of Practice Advancement and Clinical Education

Lucy Rexrode

Chapel Hill High School

Healthcare Advance Learning Technologies

Faculty Mentor: Robert Hubal, Ph.D.
Division of Practice Advancement and Clinical Education

Paul South

Panther Creek High School

The Virtual Physiological Human that will Revolutionize Medicine

Faculty Mentor: Jerry Heneghan, M.B.A.
Division of Practice Advancement and Clinical Education

Noah Ross

Carrboro High School

The Study of High School Students’ Opinions on Opioids Through Focus Groups

Faculty Mentor: Delesha Carpenter, Ph.D.
Division of Pharmaceutical Outcomes and Policy

Emily Spero

North Carolina School of Science & Math

Measuring the Geospatial Concentration of Pharmacies

Faculty Mentor: Gang Fang, Pharm.D., Ph.D.
Division of Pharmaceutical Outcomes and Policy

Kristina Cala

Top Sail High School

New Chemical Epigenetic Recruitment Platform

Faculty Mentor: Nate Hathaway, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

 

Zayn Imran

Central Cabarrus High School

Kinase Inhibitors: The Road Ahead

Faculty Mentor: Alexander Tropsha, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

 

Seth Kodikara

Piedmont High School

Assay Development for the CBX Family of Proteins

Faculty Mentor: Kenneth Pearce, Pd.D.
Division of Chemical Biology and Medicinal Chemistry

 

Haley Leversedge

Durham Academy

Using Halogens to Increase Potency at the Kappa Opioid Receptor

Faculty Mentor: Jeff Aubé, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Rebecca Ssengonzi

Green Hope High School

Examining Factor Xa Activities in Various Concentrations of Heparin

Faculty Mentor: Jian Liu, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Jerry Cai

Chapel Hill High School

Phage Engineering Vaginal Commensal Bacteria

Faculty Mentor: Sam Lai, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Robert Perna

Panther Creek High School

Improving Topical Ocular Drug Delivery through Bispecific Antibodies

Faculty Mentor: Sam Lai, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Aman Singh

Green Hope High School

Single Factor Neural Stem Cell Migration and Scaffold Fabrication/Seeding Efficiency

Faculty Mentor: Shawn Hingtgen, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Angel Wagner

East Wake Academy

Determination of Metal Binding Constants with an Orally Available Chelating Agent

Faculty Mentor: Michael Jay, Ph.D.
Division of Chemical Biology and Medicinal Chemistry

Rahul Narvekar

Panther Creek High School

nXhuman Process of Learning

Faculty Mentor: Robert Hubal, Ph.D.
Center for Innovation in Pharmacy Simulation

Emily Ruiz Escobar

Randolph Early College High School

Telepharmacy: Addressing Barriers to Medication Access in Rural Areas

Faculty Mentor: Carrie Martin Blanchard, Pharm.D., M.P.H.
Center for Medication Optimization

Jacob Gerlach

Green Hope High School

Observing Fluid Flow Through Micropillar Arrays

Faculty Mentor: Richard Superfine, Ph.D.
Department of Applied Physical Science

Faizan Mian

David W Butler High School

Programming Multicellular Interactions for Regenerative Medicine

Faculty Mentor: Ronit Freeman, Ph.D.
Department of Applied Physical Science

Aryani Pallerla

Green Hope High School

In-Situ Forming Implant for HIV Pre-Exposure Prophylaxis (PrEP)

Faculty Mentor: Rahima Benhabbour, Ph.D.
Department of Biomedical Engineering

Claire Liang

Raleigh Charter High School

Abstracting PSA Values to Determine Prostate Cancer Recurrence

Faculty Mentor: Ronald Chen, M.D., M.P.H.
Department of Radiation Oncology

Sarah Connor

North Henderson High School

Developing a Droplet PCR Based Assay to Detect Viral DNA in Plasma of Head and Neck Cancer Patients

Faculty Mentor: Gaorav Gupta, M.D., Ph.D.
Department of Radiation Oncology
UNC Lineberger Comprehensive Cancer Center

Arunangshu Chakrabarty

Carrboro High School

Identifying Crucial Amino Acid Residues in OSTα/β-Mediated Transport

Faculty Mentor: Kim Brouwer, Pharm.D., Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Herjot Cheema

Green Hope High School

Evaluating the Effect of Meropenem and Polymyxin B Against Multi-Drug Resistant Klebsiella Pneumoniae

Faculty Mentor: Gauri Rao, Pharm.D., M.S.
Division of Pharmacotherapy and Experimental Therapeutics

Fiona Gable

Franklinton High School

PK/PD Modeling and the Use of NanoBRET Technology in Cancer Research

Faculty Mentor: Yanguang Cao, Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Cecilia Lee

East Chapel High School

Genotyping Kidney Transplant Patients’ DNA for Precision Medicine

Faculty Mentor: Tim Wiltshire, Ph.D.
Division of Pharmacotherapy and Experimental Therapeutics

Suleman Qamar

Panther Creek High School

Analyzing and Simulating Drug Compounds Through the Human Body

Faculty Mentor: Angela Kashuba, Pharm.D.
Division of Pharmacotherapy and Experimental Therapeutics

Bryan Yam

Chapel Hill High School

Imaging Drug Concentrations in Hair as a Marker of Adherence: The Effect of Hair Treatments on Drug Concentrations

Faculty Mentor: Angela Kashuba, Pharm.D.
Division of Pharmacotherapy and Experimental Therapeutics

Bianca Garcia

Vernon Malone College and Career Academy

Increasing Biosimilar Use to Save Healthcare Costs

Faculty Mentor: Roy Zwahlen, J.D.
Eshelman Institute for Innovation

Avital Politi

Chapel Hill High School

Searching for Polymer Solutions to Mimic the Behavior Of Mucus

Faculty Mentor: Brian Button, Ph.D.
Marsico Lung Institute

Skylar Naderer

Chapel Hill High School

Productivity in Clinical Pharmacy

Faculty Mentor: Kayla Waldron, Pharm.D., M.S.
UNC Healthcare Department of Pharmacy

Amira Sarder

Apex High School

Productivity in Clinical Pharmacy

Faculty Mentor: Kayla Waldron, Pharm.D., M.S.
UNC Healthcare Department of Pharmacy

Areeba Khokhar

Nanoengineered Chitosan-based Hydrogel with Tunable Physical Properties as an Injectable Material for Tissue Regeneration Applications

Faculty Mentor: Rahima Benhabbour, Ph.D.
Department of Biomedical Engineering

 

Sai Harshith Rachakonda

Examining the Properties of Airway Mucins to Gain Insight into Cystic Fibrosis

Faculty Mentor: Camille Ehre, Ph.D.
Marsico Lung Institute Cystic Fibrosis Center, UNC School of Medicine

 

Evan Chan

Innovative 3D Printed Intravaginal Rings: Reengineering Multipurpose Intravaginal Rings for Prevention of HIV and Unintended Pregnancy

Faculty Mentor: Rahima Benhabbour, Ph.D.
Department of Biomedical Engineering

 

Cordelia Hume

Gender Representation in Pharmaceutical Doctoral Degrees Conferred and Pharmacy Faculty

Faculty Mentor: Jacqui McLaughlin, Ph.D.
Center for Innovative Pharmacy Education & Research (CIPhER)

Corinne Drabenstott

Engineering scFv Targeting Chemokine Receptor CXCR4 to Suppress Tumor Growth and Modulate Macrophage Polarization

Faculty Mentor: Juliane Nguyen, Ph.D.
Pharmacoengineering and Molecular Pharmaceutics (DPMP)

Halle Kahlenberg

Social Determinants of Health and Medication Adherence

Faculty Mentor: Carrie Blanchard, MPH, PharmD
Practice Advancement and Clinical Education (PACE)

Kaitlin Donovan

Study of Best Clinical Practices Involving Pediatric Patients

Faculty Mentor: Robert Hubal, Ph.D.
Practice Advancement and Clinical Education (PACE)

Lauren Sidelinger

Genetic Polymorphisms Associated with Salt Sensitivity and Blood Pressure

Faculty Mentor: Tim Wiltshire, Ph.D.
Pharmacotherapy and Experimental Therapeutics (DPET)

Ciara Darden

Delivering a Neutralizing IgM to Prevent Hematogenous Spread of Vaginally Inoculated ZIKV in Mice

Faculty Mentor: Helen Lazear, Ph.D.
Microbiology and Immunology

Bar Caspin

In Silico Alternatives to Animal Testing: A Case Study On Phototoxicity

Faculty Mentor: Alexander Tropsha, Ph.D.
Chemical Biology and Medicinal Chemistry (CBMC)

Marielle Rath

Modeling and Quantifying Anti-PEG Antibody-Mediated Clearance of PEGylated Drugs

Faculty Mentor: Sam Lai, Ph.D.
Pharmacoengineering and Molecular Pharmaceutics (DPMP)

Sheel Patel

Using Magnetic Microspheres to Measure and Manipulate Adhesions in lectin-mucin-glycan Interactions

Faculty Mentor: Richard Superfine, Ph.D.
Department of Physics and Astronomy

Daniel Zhong

Senescence Biomarker and Pathway Investigation Using Serine Hydrolase Probes

Faculty Mentor: Michael Jarstfer, Ph.D.
Chemical Biology and Medicinal Chemistry (CBMC)

Nicole Bell

Use of Phage Display for Discovery of Peptide Inhibitors for 53BP1

Faculty Mentor: Kenneth Pearce, Jr., Ph.D.
Chemical Biology and Medicinal Chemistry (CBMC)

Jennifer Spores

Evaluation of the Relationship between the Mononuclear Phagocyte System (MPS) and the Pharmacokinetics (PK) and Pharmacodynamics (PD) of a PEG-Liposomal Formulation of Docetaxel Prodrug (MM-310) in Patients

Faculty Mentor: Bill Zamboni, Pharm.D., Ph.D.
Pharmacotherapy and Experimental Therapeutics (DPET)

Sabarish Srinivasan

Ultrasensitive Digital PCR Assay to Quantify Plasma Circulating HPV16 DNA in Oropharyngeal Cancer

Faculty Mentor: Gaorav Gupta, M.D., Ph.D.
Lineberger Comprehensive Cancer Center
Department of Radiation Oncology
Department of Biochemistry and Biophysics

Olivia Andrews

Bacteriophage Engineering for Targeted Bacterial Population Editing

Faculty Mentor: Sam Lai, Ph.D.
Pharmacoengineering and Molecular Pharmaceutics (DPMP)

Justin Zhao

Modeling and Simulation for Emicizumab Dose Optimization

Faculty Mentor: Carter Cao, Ph.D.
Pharmacotherapy and Experimental Therapeutics (DPET)

Isaiah McLeod

The Impact of Blockchain

Faculty Mentor: Roy Zwahlen, J.D.
Eshelman Institute for Innovation (EII)

Patrick Deegan

Creating Molecules to Kickstart Healthier Outcomes

Faculty Mentor: Ronit Freeman, Ph.D.
Applied Physical Sciences (APS)